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KMID : 1100220180170010037
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Dementia and Neurocognitive Disorders
2018 Volume.17 No. 1 p.37 ~ p.40
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Emerging of Explosive Speech after Olanzapine in Multiple System Atrophy Patient
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Kim Yong-Sung
Kim Seung-Jae
Lee Jong-Min
Kim Hee-Jin
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Abstract
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Background: Cerebellum has an important role in sensorimotor control including speech. Multiple system atrophy (MSA) is a sporadic and rapidly progressive neurodegenerative disorder that presents with autonomic failure in combination with Parkinsonism or cerebellar ataxia.
Case Report: We report a case of MSA-cerebellum subtype associated with emergence of irreversible explosive speech following olanzapine therapy.
Conclusions: Further investigation into speech problems in MSA according to subtype and disease severity is needed, and side effects of olanzapine therapy should also be considered.
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KEYWORD
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Antipsychotic Agents, Multiple System Atrophy, Speech
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